We provide integrated building services engineering for GMP-regulated and technically demanding environments. With in-house specialists across all disciplines, we coordinate design, planning and delivery through a single point of contact.
Our services include HVAC, heating, cooling, sanitary systems, electrical engineering, building automation and pharmaceutical utility systems. We also integrate environmental monitoring and clean utilities such as Water for Injection (WFI), Purified Water (Aqua Purificata), clean steam, pure steam and process gases into the overall concept.
The result is a well-engineered, energy-efficient and GMP-compliant solution under one roof.
We design and deliver HVAC systems for GMP-regulated environments in line with current industry standards, legal requirements and relevant guidelines. Our solutions support stable processes, reliable cleanroom performance and efficient operation.
Our services include:
Cleanroom HVAC concepts
Pressure cascades and airflow strategies
Temperature and humidity control
Energy-efficient system design
Implementation support and commissioning
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We plan and implement customized extraction and dust collection solutions for your specific applications—fully taking into account GMP requirements, occupational safety and explosion protection. From capture at the point of generation and suitable separation and filtration technology through to safe exhaust air routing, we develop tailored concepts for a controlled and hygienic production environment.
The following are used, among others:
With our experienced specialist engineers, we cover the full spectrum of planning and implementation in the areas of steam, heating, cooling and sanitary systems. From needs analysis and design and sizing through to implementation, we develop technically sound and energy-efficient utility concepts. In doing so, we consider process requirements as well as cost-effectiveness, sustainability and regulatory specifications.
In the areas of high and low voltage (telecommunications and communications engineering), we plan and implement holistic, safe and standards-compliant systems—tailored to your technical and regulatory requirements.
In the field of building automation and instrumentation and control (IC), we cover the full spectrum from planning and integration through to implementation. The goal is transparent, stable and energy-efficient control of your building services and process-related systems.
Our scope of services includes, among others:
We deliver end-to-end automation solutions that increase operational reliability, optimize energy consumption and reliably meet regulatory requirements.
As a qualification-relevant discipline, we plan and install manufacturer-independent pharmaceutical environmental monitoring systems in accordance with applicable European and international regulations.
Our scope of services includes, among others:
As part of commissioning activities, the following are carried out:
These activities are carried out in coordination with those responsible for Qualification / Validation.
We plan and implement compressed air and gas systems to meet the highest pharmaceutical requirements. In doing so, we take into account specifications regarding particle content, residual moisture and residual oil, as well as regulatory requirements and qualification needs. In addition to conventional process compressed air, we also design high-purity gas and specialty gas supplies—including treatment, storage, distribution and monitoring.
As part of our projects, we plan and implement firefighting systems—tailored to use, risk analysis and regulatory requirements.
These include, among others:
Integration into overarching safety concepts—such as fire alarm systems (FAS), smoke aspiration systems (SAS) or building radio systems (BOS)—is carried out holistically and in compliance with standards. This is how we deliver technically coordinated, authority-approvable and operationally reliable fire protection solutions from a single source.
We support the complete implementation of your project—technically across all trades and organizationally through experienced site managers. Our specialist engineers monitor technical execution, coordinate interfaces and ensure that planning, quality and schedules are consistently adhered to. In parallel, we manage on-site processes, facilitate coordination between trades and ensure transparency for all project stakeholders. This ensures structured, quality-assured and on-time execution through to successful handover.
SPIE LSE commissions cleanrooms with its own staff and qualified measurement technology. Our specialists are organizationally assigned to the Qualification department and have extensive experience in GMP-regulated environments. This ensures that commissioning, functional tests and measurement evidence transition seamlessly into subsequent qualification activities. In this way, we ensure a structured, standards-compliant and technically sound transfer of your systems into routine operation.
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We cover all planning phases—from traditional 2D planning and 3D modeling through to integrated BIM-based project delivery.
Due to the wide range of requirements for different CAD and BIM systems, we use a broad toolset and adapt our methodology flexibly to project size and complexity.
Systems and methods used:
This ensures consistent, clash-free and transparent planning—from the initial concept idea through to detailed design ready for execution.
As part of our work as a general planner, we prepare all functional planning and specification documents that serve as a reliable basis for tendering, award and contract.
These include, among others:
In addition, we prepare schematics, floor plans as well as 3D models and visualizations to present technical interrelationships transparently and define interfaces clearly. This results in complete, clear and contractually robust documentation—as a solid basis for smooth project execution.
Expansion of Plant III with a 4-story extension + basement + technical center for office and laboratory areas as well as the expansion of the fully automated high-bay warehouse – GFA 6,440 m²
Dr. Graeub is implementing the separation of media, purified media, and electrical supply from Janssen at the site following the acquisition of the production facility
Authority engineering, installation planning, and turnkey
implementation of
In the existing Building J, the production areas for TPN, sterile, cytostatics and genetic engineering are to be implemented on the ground floor, and the required technical areas in the basement, GFA 2,000 m²
Concept + design and approval planning, all trades –
See our services and experience for yourself.
Bereichsleiter Digitalisierungslösungen
Pfullendorf, Niedernberg
Abteilungsleiter Vertrieb und Geschäftsentwicklung
Pfullendorf
Bereichsleiter Verfahrenstechnik und Leichtbaurobotik & Intralogistik
Dormagen
Bereichsleiter Montage & Verlagerung
Dormagen, Gescher, Dresden, Merseburg
Sales & Technical
Furnace & Refractory Inspection Specialist
#SPIE FIOS
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